Disease Model iPSCs-SomaxBio

Disease Model iPSCs

Catalog No.：

详见产品信息

Specification：

1×10⁶ cells/vial

Storage Conditions：

Liquid nitrogen

Product Introduction：

Somax Disease Model iPSCs are constructed by knocking out/mutating specific genes in healthy donor-derived iPSCs using CRISPR/Cas9 technology. They share similar morphological characteristics and gene expression patterns with healthy donor-derived iPSCs.

Product Advantages

A variety of disease model iPSCs have been constructed, providing isogenic wild-type, heterozygous, and homozygous cell lines. Disease models include:

Tuberous Sclerosis Complex Model

Epilepsy Model

Alzheimer's Disease Model

Parkinson's Disease Model

Polycystic Kidney Disease Model

Obesity Model

Operation Procedures and Precautions

After receiving the cells, observe and record any signs of thawing during transportation and the integrity of the cryovials.

Transfer to liquid nitrogen immediately; temporary storage at -80℃ is allowed, but prolonged storage is strictly prohibited.

Recommended recovery culture system for cryovials: 2 wells of a 6-well plate.

Application Scope：

This product is for research use only and not for clinical treatment or other purposes.

Cell Characteristics

Monoclonal morphology (4X)

Confluent clone morphology (4X)

Product Information

Cell Type	Catalog No.	Specification
Tuberous Sclerosis Complex Model iPSC-TSC1-KO	JY02-02-001	1×10⁶ cells/via
Epilepsy Model iPSC-KCNQ2-KO	JY02-02-009	1×10⁶ cells/via
Epilepsy Model iPSC-KCNQ2 c.1742G>A	JY02-01-005	1×10⁶ cells/via
Epilepsy Model iPSC-KCNQ2 c.807G>A	JY02-01-010	1×10⁶ cells/via
Epilepsy Model iPSC-SCN1A c.2801T>A	JY02-01-013	1×10⁶ cells/via
Epilepsy Model iPSC-SCN1A-KO	JY02-02-012	1×10⁶ cells/via
Epilepsy Model iPSC-SCN1A c.2797C>T	JY02-01-014	1×10⁶ cells/via
Alzheimer's Disease Model iPSC-APP c.2010-2011inv	JY02-01-001	1×10⁶ cells/via
Alzheimer's Disease Model iPSC-APP c.2149G>A	JY02-01-012	1×10⁶ cells/via
Alzheimer's Disease Model iPSC-PSEN1-EXON9-KO	JY02-02-011	1×10⁶ cells/via
Alzheimer's Disease Model iPSC-PSEN1 c.313T>C	JY02-01-008	1×10⁶ cells/via
Parkinson's Disease Model iPSC-SNCA c.157G>A	JY02-01-023	1×10⁶ cells/via
Parkinson's Disease Model iPSC-LRRK2 c.6055G>A	JY02-01-015	1×10⁶ cells/via
Polycystic Kidney Disease Model iPSC-PKD2-KO	JY02-02-007	1×10⁶ cells/via
Obesity Model iPSC-LEPR-KO	JY02-02-017	1×10⁶ cells/via
Obesity Model iPSC-MC4R-KO	JY02-02-037	1×10⁶ cells/via
Obesity Model iPSC-SRA1-KO	JY02-02-021	1×10⁶ cells/via
Obesity Model iPSC-CYP2E1-KO	JY02-02-029	1×10⁶ cells/via

iPSC Cell Products
Other Products

Healthy Donor-Derived iPSCs Disease Model iPSCs Fluorescently Labeled iPSCs (GFP/mCherry) NGN2-Stable iPSCs

Questions

When thawing and seeding iPSC cells, most of them are found to be in a single-cell morphology and hardly attach after 24 hours. What is the cause, and how should it be handled? Precautions for iPSC cell passaging Cells exhibit vacuolization. The significance of establishing iPSC lines from the blood of patients with rare diseases