PSC-Derived Neural Progenitor Cells-SomaxBio

PSC-Derived Neural Progenitor Cells

Catalog No.：

JY03-02-03

Specification：

1×106 cells/vial

Storage Conditions：

Liquid Nitrogen

Product Introduction：

Neural Progenitor Cells (NPCs) are central nervous system progenitor cells generated via directed differentiation of human induced pluripotent stem cells (iPSCs). They feature self-renewal capability and multipotent differentiation potential, and can efficiently differentiate into functional neural cells including neurons, astrocytes and oligodendrocytes. This product needs directed induction with SomaBio Neural Precursor Cell Differentiation Kit (Catalog No.: R3-02-05). The standardized differentiation protocol is easy to operate, allowing stable generation of high-purity and high-viability neurons.

Product Advantages

1. High Purity and Specificity: Cells highly express classic neural progenitor cell markers Nestin, SOX2 and PAX6 with a positive rate ≥95%, while exhibiting low expression of neuronal markers MAP2 and TUJ1, without contaminating heterologous cells.

2. Efficient Directed Differentiation: Capable of efficient differentiation into mature neurons that specifically express neuronal markers MAP2 and TUJ1 (β‑III tubulin). The differentiation efficiency is ≥90%, and the resulting neurons possess typical electrophysiological functions and synapse-forming capacity.

3. Wide Range of Applications: Suitable for mechanistic studies of neurodegenerative diseases (Alzheimer’s disease, Parkinson’s disease), neurodevelopmental disorders, spinal cord injury, etc. It supports high-throughput drug screening, toxicity testing, cell therapy research and neuroregenerative medicine, serving as a reliable cellular tool.

Operation Procedures and Precautions

Upon cell receipt, inspect and record whether the cells show any signs of thawing during transit and verify the integrity of cryovials.

Transfer to liquid nitrogen immediately. Temporary storage in a -80°C freezer is permitted; long-term storage at this temperature is prohibited.

Take photos for record and provide immediate feedback if any issues are found.

Scope of Application

This product is for research use only and is not intended for clinical therapy or other purposes.

Cell Characteristics

Morphology of Neural Progenitor Cells (NPCs)

Neural Progenitor Cell Marker Identification, NESTIN, 10X

Neural Progenitor Cell Marker Identification, PAX6, 10X

Neural Progenitor Cell Marker Identification, SOX1, 20X

Bright-field image of neurons, 10X

Class III β-tubulin，10X

MAP2，10X

Product Information

Product	Catalog No.	Specification
iPSC-Derived Neural Progenitor Cells	JY03-02-03	1×10⁶/vial

iPSC-Derived Cells
Other Products

PSC-Derived Neural Progenitor Cells iPSC-Derived Retinal Pigment Epithelial Cells iPSC-Derived Cardiomyocytes iPSC-Derived Mesenchymal Stromal Cells iPSC-Derived Endothelial Cells iPSC-Derived Renal Podocytes

Questions

When thawing and seeding iPSC cells, most of them are found to be in a single-cell morphology and hardly attach after 24 hours. What is the cause, and how should it be handled? Precautions for iPSC cell passaging Cells exhibit vacuolization. The significance of establishing iPSC lines from the blood of patients with rare diseases